I have been a TB and HIV clinician and researcher for the past 30 years. I helped design and implement TB and HIV treatment trials through the Tuberculosis Trials Consortium, the ACTG, and the CPCRA / INSIGHT. I have also been a member of TB treatment guideline panels for the United States.
Despite their frequency and impact on treatment outcomes, international guidelines frequently lack recommendations for AE management. Treatment guideline should provide recommendations on management of adverse events, even if the evidence for doing so is of low quality. Research on prevention and management of adverse events should be a priority for improving the patient’s experience and the outcomes of tuberculosis treatment. Greater attention to ease of use of recommendations for adverse event management would help clinical staff.
Source: Conference 2024