Biography

Dr Sarah Nyangu holds a Bachelor of Science in Human Biology (BScHB) and Bachelor of Medicine and Bachelor of Surgery (MBCHB) from University of Zambia, and an MSc Epidemiology from London School of Hygiene and Tropical Medicine. They worked as medical officer and clinical research manager to execute Stop TB Partnership (TB-REACH projects Wave 7 & 10) and FIND projects in Zambia. They are currently a clinician-scientist at the South African Tuberculosis Vaccine Initiative (SATVI), University of Cape Town, working on analysis of radiological methodologies for screening and triage of asymptomatic and symptomatic TB in the RePORT South Africa Network.

Expertise

TB Diagnostics
Public Health

Key Impacts

Chest radiographic TB screening using human vs. artificial intelligence reads in asymptomatic adult household contacts in South Africa

Among TB-exposed household contacts tested regardless of symptoms, dCXR readings by human and qTrack showed good agreement. qTrack sensitivity was marginally better than human readers, but below the WHO target product profile sensitivity for a screening test (90%), for asymptomatic and symptomatic TB screening.

Source: Conference 2024

Research Summaries

PAPER
Hidden inflammation: asymptomatic tuberculosis shares blood signatures with symptomatic disease
29 Oct 2025