Biography

Megan Murray, MD, MPH, ScD is an epidemiologist and an infectious disease physician with over 25 years of experience in the management of TB programs and TB epidemiology, as well as the transmission dynamics of emerging infectious diseases. She is a Professor of Global Health and Social Medicine and an Associate Professor of Medicine at Harvard Medical School, where she leads the Global Health Research Core, a multidisciplinary group of researchers who work with the Global Health Delivery Partnership faculty and staff to develop its mission to link research to the teaching and service activities of the Partnership.

Expertise

TB Diagnostics
Public Health

Key Impacts

Isoniazid preventive therapy (IPT) and TB infection in intrahousehold contacts: Results from a cohort in Peru

Although IPT is known to protect TST positive children from TB disease progression, here we find that IPT is associated with a modestly higher rate of TST conversion. This finding raises the possibility that IPT enhances the immune response to TB infection, paradoxically leading to increased TST induration size at the same time that it protects against TB disease progression.

Source: Conference 2024

Research Summaries