Biography

Liu Chang is a chief physician in the Department of Thoracic Surgery at Shenyang Chest Hospital. He also serves as a research assistant in the Department of Thoracic Surgery and secretary of the Shenyang Clinical Research Center for Lung Cancer. His clinical and research work focuses on the diagnosis and treatment of thoracic surgical diseases, particularly tuberculosis-related thoracic conditions, such as tuberculous empyema. His scientific research emphasizes the surgical management and pathophysiological mechanisms of tuberculosis-associated thoracic diseases, aiming to improve outcomes for patients with complex pleural and pulmonary tuberculosis.

Expertise

TB Diagnostics
Public Health

Key Impacts

Application of targeted next-generation sequencing (tNGS) in diagnosis and drug resistance prediction of extrapulmonary TB

tNGS is an effective diagnostic tool, which can be used for rapid diagnosis of EPTB. Its high sensitivity and specificity in the diagnosis of EPTB make it an important supplement to traditional diagnostic methods. The variability of drug resistance diagnosis needs to be further verified and solved in clinical application, and the best application mode of drug resistance diagnosis in EPTB management should be explored.

Source: Conference 2024

Research Summaries

PAPER
New genetic clue to resisting tuberculosis infection
07 Mar 2026