Biography

Dr Celso Khosa is Director of the Centro de Investigação e Treino em Saúde da Polana Caniço (CISPOC) at the Instituto Nacional de Saúde (INS) in Maputo, Mozambique. A medical doctor and researcher, his work focuses on tuberculosis, HIV, and related comorbidities, with strong interests in operational research, digital health, and health systems strengthening. He has led several clinical trials and implementation studies on TB diagnostics, shorter treatment regimens, and post-TB care. Dr Khosa also contributes to public health research training and serves as a senior lecturer and advisor on research capacity building in Mozambique.

Expertise

TB Diagnostics
Public Health

Key Impacts

Designing a digital clinical decision support system to strengthen implementation of treatment decision algorithms for childhood TB in Zambia and Mozambique

Developing digital CDSS tools to support TDA implementation in LMICs requires more than technological innovation; it demands stakeholder co-design, adaptation taking into consideration structural barriers such as electricity issues or internet issues and embedded capacity-building strategies adapted to the digital literacy of HCWs. Addressing these factors holistically is crucial for digital CDSS tools to effectively enhance TDA uptake in LMICs.

Source: Conference 2024
Factors affecting the performance of chest X-ray artificial intelligence-based computer-aided diagnosis for TB in a primary health centre

AI met the WHO TPP criteria without threshold calibration. The likelihood of incorrect AI results was higher in those with low BMI, past TB history and HIV. More research is needed to corroborate the findings and to investigate if these subgroups will benefit from focused calibration.

Source: Conference 2024
Smarter decision, earlier diagnosis: The evolving landscape of pediatric TB

Impact details available upon request.

Source: Conference 2024

Research Summaries