PAPER 16 Dec 2025 Global

High ICU death rate found at Ethiopian hospital, head injuries lead admissions

Amanuel Sisay Endeshaw reports a 31.3% ICU mortality at Tibebe Ghion Specialized Hospital, with head injury the top reason for admission and death.

Intensive care services are scarce across much of sub‑Saharan Africa, even as the number of critically ill patients rises with urbanization, new epidemics and wider hospital access. To better understand what happens to the sickest patients in one large regional hospital, researchers led by Amanuel Sisay Endeshaw reviewed who was admitted to the adult ICU at Tibebe Ghion Specialized Teaching Hospital and how those patients fared. They looked back through the unit’s admission log, covering every recorded adult ICU admission between January 1, 2019 and June 30, 2020. The main aim was simple: measure outcomes after ICU admission and identify where care could improve. By using routinely recorded information this study provides a snapshot of critical care in a low‑resource setting, showing which conditions fill beds, how many patients need machines like ventilators, and how many survive their ICU stay. The work offers a starting point for hospitals and health planners seeking to reduce deaths in intensive care.

The team used an institutional retrospective cross‑sectional design and extracted data from 454 ICU records. Data entry, editing and analysis were done in Stata software (version14). To examine which factors were linked with dying in the ICU they ran logistic regression and presented survival over time with Kaplan‑Meier (KM) curves. The overall ICU mortality was 31.3%. The most common reasons for admission were head injury (19.6%), non‑tuberculosis respiratory problems (11.89%), post abdominal surgeries (8.37%) and myocardial infarction (6.82%). Just over a third (36.3%) of patients received mechanical ventilation. In adjusted analysis, several measures were associated with ICU death: time spent in ICU (OR = 1.37 [95% CI, 1.16 – 1.62]; P = 0.000), needs for mechanical ventilation (OR = 0.18 [95% CI, 0.12 – 0.28]; P = 0.000), days on mechanical ventilation (OR = 0.73 [95% CI, 0.61 – 0.87]; P = 0.001) and non‑infection status (OR = 0.45 [95% CI, 0.24 – 0.69]; P = 0.000).

These findings highlight practical priorities for reducing deaths in a resource‑constrained ICU. A 31.3% mortality rate means nearly one in three ICU patients did not survive their stay; head injury was the dominant cause of both admission and death, pointing to the importance of trauma prevention, timely surgery and specialized critical care for head trauma. The frequent use of mechanical ventilation and its association with outcomes indicates that ventilators, trained operators and protocols for ventilated patients are central to care quality. The links seen with infection status and length of ICU stay suggest infection control and efficient pathways out of intensive care could also lower mortality. While the study is based on routine chart data from one hospital, it identifies clear targets for investment: trauma systems, ventilator capacity and staff training, infection prevention, and perhaps better triage to match patients to the level of care they need. Policymakers and hospital leaders can use these local data to plan where modest resources might have the biggest impact.

Public Health Impact

The study points to actionable priorities—trauma care, infection control, ventilator resources and ICU staffing—to reduce deaths in a low‑resource ICU. Local hospitals and health planners can use these findings to target investments and training.

Intensive care
ICU mortality
Tibebe Ghion Specialized Hospital
mechanical ventilation
head injury
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Author: Amanuel Sisay Endeshaw

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